Noxopharm White Paper

NOXOPHARM L IMITED White Paper b Contents (i) Bray F, Laversanne M, Weiderpass E, Soerjomataram I. The ever- increasing importance of cancer as a leading cause of premature death worldwide. Cancer. In press. https://doi.org/10.1002/ cncr.33587 (ii) Global, regional, and national sepsis incidence and mortality, 1990–2017: analysis for the Global Burden of Disease Study Rudd, Kristina E et al. The Lancet, Volume 395, Issue 10219, 200 – 211. https://doi.org/10.1016/S0140-6736( 19)32989-7 Introduction ...a new type of drug Veyonda® is a new concept in therapeutics – a drug designed to recalibrate the body’s immune system, with cancer and septic shock the two outstanding examples of what happens when the immune system becomes unbalanced. Of the estimated 55 million people who die each year globally from disease, it is estimated that approximately 10 million die from cancer (i) and approximately 10 million from septic shock (ii) due to infectious diseases. To that last figure, the current pandemic looks to be adding an extra 2 million deaths p.a. from septic shock. The connection between the two apparently disparate conditions is abnormal behaviour of the immune system. Cancer Cancer is only able to survive by manipulating the body’s immunosurveillance systems to avoid immune attack. Septic shock Septic shock results from the body mounting an inappropriately excessive immune response to tissue injury coming from infections (viral, bacterial) and trauma. Idronoxil, the active ingredient in Veyonda , possesses the unique dual action of being able to re-balance and re-calibrate the immune system regardless of whether the unbalancing is the result of an under-active (cancer) or over- active (septic shock) immune response. 1 Veyonda® – the basics 2 Veyonda® – how it works 4 Veyonda® – anti-cancer effects 6 Veyonda® – anti-inflammatory effects 8 Veyonda® – oncology program overview 9 Veyonda® – DARRT program 11 Veyonda® – LuPIN program 13 Veyonda® – CEP program 15 Veyonda® – IONIC program 17 Veyonda® – NOXCOVID program Disclaimer: Veyonda is currently not approved in Australia or any other country