Noxopharm White Paper

NOXOPHARM L IMITED White Paper 4 From these three biochemical outcomes, come the following functional outcomes, falling into two broad categories referred to as oncotoxic and immunological outcomes. Veyonda® – anti-cancer effects Veyonda’s anti-cancer functions, via inhibition of ENOX2, have three mainstream biochemical outcomes: • protein thiol-disulfide exchange • ceramide levels • S1P levels. Decreased protein thioldisulfide exchange Increased ceramide Cell growth cell membrane budding protein folding DNA repair autophagic repair angiogenesis Immune cell activation Immune cell migration Mitotic arrest Apoptosis insulin resistance Decreased S1P ONCOTOXIC outcomes IMMUNOLOGICAL outcomes