Professor Michael Gantier leads the Nucleic Acids and Innate Immunity laboratory at the Hudson Institute of Medical Research. With over 20 years of expertise in RNA biology, his work focuses on harnessing RNA to modulate innate immune responses for therapeutic benefit.
Trained as a biological engineer in France, he completed his PhD at University College Dublin before moving to Australia to work with Prof Bryan Williams on RNA therapeutics and innate immunity.
Since establishing his independent laboratory in 2015, Prof Gantier’s team has uncovered fundamental immunosuppressive mechanisms of RNA therapeutics, culminating in the discovery that RNA cleavage products mimic natural immune checkpoints against autoimmunity (Alharbi et al., Nature Immunology 2026).
In collaboration with Noxopharm, his group has developed a novel class of ultra short RNA based anti-inflammatory agents that have recently completed Phase 1 clinical trials (Sapkota et al. bioRxiv 2026).
Prof Gantier has received multiple international awards, published extensively in leading journals with over 85 publications to date (including Nature, Cell, Nature Immunology, Nature Communications, Nucleic Acids Research etc), and currently serves as Associate Editor of Molecular Therapy Nucleic Acids.
